Resources
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Characterising Protein Structure with HDX-MS: Improving Resolution with IMS-MS and Electron-based Fragmentation
Speaker Presentation Dhungana Suraj Waters Corporation 2022
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Revolutionizing Protein Higher Order Structural Analysis
Speaker Presentation Chea Emily GenNext Technologies 2022
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Laser
-Free Oxidation (Fox
™)
Hydroxyl Radical Protein
Footprinting (HRPF) for mAb
Drug Development
Speaker Presentation Chea Emily GenNext Technologies 2022
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Best Practices for Aggregate
Quantitation of Antibody
Therapeutics by Sedimentation Velocity
Analytical Ultracentrifugation
Speaker Presentation Brenowitz Michael Albert Einstein College of Medicine 2022
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Combining Refoldability Assessment and Molecular Dynamics Simulations to Select Aggregation-Resistant Antibodies
Speaker Presentation Berner Carolin VIB-VUB Center for Structural Biology 2022
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Regulatory Aspects of Manufacturing and Control of CAR-T cells, Game-changing Autologous Immunotherapy Products
Speaker Presentation Hoefnagel Marcel Medicines Evaluation Board 2022
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Invalid Rates Workshop
Workshop Report Kennett Watzig Sänger-van de Griend 2015
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An Opportunity for Industry-Academia Partnership - Training the Next Generation of Industrial Researchers in Characterizing Higher Order Protein Structure
Case Study Bain Brenowitz Roberts 2016
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Impact of a Formulation Change on the Higher Order Structure and Stability of a mAb
Case Study Gruia et al. 2014
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Detecting Reversible Concentration-Dependent Self-Association in a Monoclonal Antibody and a Preliminary Investigation to Eliminate It
Case Study Wei et al. 2015
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Technical Decision-Making with Higher Order Structure Data - Starting a New Dialogue
Case Study Gabrielson Weiss 2016
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Higher Order Structure Characterization During Protein Therapeutic Candidate Screening
Case Study Jiang et al. 2015
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Utilization of Differential Scanning Calorimetry to Elucidate Critical Protein Structural Changes Resulting from Oxidation
Case Study Arthuer Dinh Gabrielson 2015
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Perspectives on Higher Order Structure Characterization From the Biopharmaceutical Industry
Case Study Weiss et al. 2015
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Specific Binding of a Nonionic Detergent Perturbs Higher Order Structure of a Therapeutic Monoclonal Antibody
Case Study Budyak Doyle Weiss 2014
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Physicochemical In-use Studies: Industry Experts Insights
Speaker Presentation de Jong Genentech Liu Seagen 2022
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Bringing MAM to the Next Level: Thermo Scientific MAM 2.0
Speaker Presentation Yang Hao Thermo Fisher Scientific 2022
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Regulatory Reliance – a Future Reality for CMC?
Speaker Presentation Wilkinson Diane AstraZeneca 2022
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mAbs to Empowered Antibodies -Strategies beyond IgG
Speaker Presentation Shapiro Marjorie CDER 2022
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Project ORBIS: Opportunities and Challenges
from the CMC Review of Biologics at Health
Canada
Speaker Presentation Rowlandson Karen Health Canada 2022